Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 4/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166698 | 1.00 | GSK3B (0.60) | GSK3BDYRK1ANOTUMMTORABL1 | |
| SCHEMBL30381667 | 0.85 | DYRK1A (0.54) | GSK3BDYRK1AABL1WNT3ASYK | |
| SCHEMBL29650022 | 0.83 | GSK3B (0.61) | GSK3BDYRK1AMTORABL1NPC1 | |
| SCHEMBL20227778 | 0.83 | ABL1 (0.59) | GSK3BDYRK1AMTORABL1MEN1 | |
| SCHEMBL30381790 | 0.83 | GSK3B (0.50) | GSK3BDYRK1AABL1TRPV1MAPK1 | |
| SCHEMBL28166709 | 0.83 | GSK3B (0.61) | GSK3BDYRK1ANOTUMABL1MAPK1 | |
| SCHEMBL4302469 | 0.83 | GSK3B (0.61) | GSK3BDYRK1AMTORABL1NPC1 | |
| SCHEMBL7093982 | 0.83 | GSK3B (0.47) | GSK3BDYRK1ANOTUMMTORABL1 | |
| SCHEMBL7093981 | 0.83 | GSK3B (0.47) | GSK3BDYRK1ANOTUMMTORABL1 | |
| SCHEMBL29710317 | 0.82 | DYRK1A (0.60) | GSK3BDYRK1AMTORABL1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062804-A | 1, 3-substituted cyclobutyl derivatives and their use | 诺华股份有限公司 | 2023-11-14 | — | — | CN | disclosed |