Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.66 |
| ▸ | BDNF | P23560 | 3/20 | 0.52 |
| ▸ | MDK | P21741 | 3/20 | 0.52 |
| ▸ | PTN | P21246 | 2/20 | 0.52 |
| ▸ | BMP2 | P12643 | 3/20 | 0.46 |
| ▸ | VEGFA | P15692 | 3/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.46 |
| ▸ | SHH | Q15465 | 2/20 | 0.46 |
| ▸ | IFNG | P01579 | 2/20 | 0.44 |
| ▸ | PF4 | P02776 | 1/20 | 0.44 |
| ▸ | CCL2 | P13500 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | BMP6 | P22004 | 1/20 | 0.44 |
| ▸ | CCL11 | P51671 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.44 |
| ▸ | SERPINC1 | P01008 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | FGF2 | P09038 | 3/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29614646 | 0.99 | F10 (0.67) | F10BDNFMDKPTNBMP2 | |
| Hydrochloric Acid SCHEMBL28233049 | 0.99 | F10 (0.66) | F10BDNFMDKPTNBMP2 | |
| SCHEMBL28227554 | 0.99 | F10 (0.68) | F10BDNFMDKPTNBMP2 | |
| SCHEMBL11557 | 0.99 | F10 (0.68) | F10BDNFMDKPTNBMP2 | |
| SCHEMBL543122 | 0.99 | F10 (0.68) | F10BDNFMDKPTNBMP2 | |
| SCHEMBL28294039 | 0.97 | F10 (0.66) | F10BDNFMDKPTNBMP2 | |
| Potassium Ion SCHEMBL28270668 | 0.97 | F10 (0.66) | F10BDNFMDKPTNBMP2 | |
| SCHEMBL28297524 | 0.97 | F10 (0.66) | F10BDNFMDKPTNBMP2 | |
| Hydrochloric Acid SCHEMBL28179031 | 0.97 | F10 (0.66) | F10BDNFMDKPTNBMP2 | |
| Hydroxyamine SCHEMBL28122321 | 0.97 | F10 (0.66) | F10BDNFMDKPTNBMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107091869-A | Copper nano-particle/pyrocatechol violet/carbon nano tube modified electrode and its application | 南京理工大学 | 2017-08-25 | — | — | CN | claimed |
| CN-105030702-B | One kind sodium pharmaceutical composition containing heparin and preparation method thereof | 马鞍山丰原制药有限公司 | 2019-01-18 | — | — | CN | disclosed |
| CN-107091869-A | Copper nano-particle/pyrocatechol violet/carbon nano tube modified electrode and its application | 南京理工大学 | 2017-08-25 | — | — | CN | disclosed |