Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19750174 | 0.81 | CPB2 (0.46) | CYP1A2TYRPKMRECQLALDH1A1 | |
| SCHEMBL6905691 | 0.80 | CYP1A2 (0.35) | CYP1A2TYRHSD17B10PKMSLC1A3 | |
| SCHEMBL27634976 | 0.80 | CYP1A2 (0.39) | CYP1A2TYRHSD17B10PKMCYP3A4 | |
| SCHEMBL27974517 | 0.77 | CYP1A2 (0.46) | CYP1A2TYRUSP2HSD17B10PKM | |
| SCHEMBL44187 | 0.75 | CYP1A2 (0.45) | CYP1A2TYRUSP2HSD17B10PKM | |
| SCHEMBL60911 | 0.75 | CYP1A2 (0.45) | CYP1A2TYRUSP2HSD17B10PKM | |
| SCHEMBL4727798 | 0.75 | CYP1A2 (0.45) | CYP1A2TYRPKMSLC1A3CPB2 | |
| SCHEMBL14798187 | 0.75 | CYP1A2 (0.45) | CYP1A2TYRUSP2HSD17B10PKM | |
| SCHEMBL4726518 | 0.75 | CYP1A2 (0.45) | CYP1A2TYRPKMSLC1A3CPB2 | |
| SCHEMBL9064610 | 0.75 | PTPRC (0.38) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107090038-A | Anti- C MET antibody formulations | 霍夫曼-拉罗奇有限公司 | 2017-08-25 | — | — | CN | disclosed |