Pyridine

Pyridine

SCHEMBL28168570

CNCCN1CCNCC1.c1ccncc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.48
ALDH1A1 P00352 1/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
CARM1 Q86X55 13/20 0.46
PRMT6 Q96LA8 13/20 0.46
PRMT8 Q9NR22 3/20 0.46
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
PRMT1 Q99873 1/20 0.41
SIGMAR1 Q99720 2/20 0.39
RAD52 P43351 1/20 0.39
TMEM97 Q5BJF2 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL681608 0.84 CARM1 (0.62) CYP3A4CYP2D6L3MBTL1ALDH1A1ALOX15
Pyridine SCHEMBL1514812 0.81 CYP3A4 (0.44) CYP3A4CYP2D6L3MBTL1ALDH1A1ALOX15
Benzene SCHEMBL28877638 0.78 SIGMAR1 (0.47) CYP3A4CYP2D6L3MBTL1ALDH1A1ALOX15
Pyridine SCHEMBL28152800 0.78 SIGMAR1 (0.47) CYP3A4CYP2D6L3MBTL1ALDH1A1ALOX15
Pyridine SCHEMBL28287143 0.77 CYP3A4 (0.44) CYP3A4CYP2D6L3MBTL1ALDH1A1ALOX15
Pyridine SCHEMBL28076683 0.77 CYP3A4 (0.44) CYP3A4CYP2D6L3MBTL1ALDH1A1ALOX15
Pyridine SCHEMBL28209413 0.77 CYP3A4 (0.44) CYP3A4CYP2D6L3MBTL1ALDH1A1ALOX15
SCHEMBL2910907 0.77 CARM1 (0.65) CYP3A4CYP2D6CARM1PRMT6PRMT8
Pyridine SCHEMBL28141133 0.77 SIGMAR1 (0.41) CYP3A4CYP2D6L3MBTL1ALDH1A1ALOX15
Pyridine SCHEMBL28212314 0.77 SIGMAR1 (0.45) CYP3A4CYP2D6L3MBTL1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104968656-B autotaxin inhibitors 诺华股份有限公司 2017-08-11 CN disclosed