Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 5/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL28801318 | 0.90 | KDM4E (0.37) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29140533 | 0.87 | MCHR1 (0.38) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28801307 | 0.83 | PPARG (0.30) | — | |
| SCHEMBL28019878 | 0.81 | NR1H2 (0.37) | — | |
| SCHEMBL1945083 | 0.80 | ALDH1A1 (0.36) | MEN1LMNAMAPTKMT2A | |
| SCHEMBL27742194 | 0.80 | NR1H2 (0.35) | TLR8 | |
| Iodide SCHEMBL2313827 | 0.79 | PDE5A (0.38) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28493240 | 0.79 | RARB (0.40) | CYP1A2CYP2C9CYP2C19CYP19A1CYP3A4 | |
| SCHEMBL28436255 | 0.79 | RARB (0.40) | CYP1A2CYP2C9CYP2C19CYP19A1CYP3A4 | |
| SCHEMBL21932593 | 0.79 | CYP1A2 (0.34) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011349-A | The synthetic method of benzophenanthrene decane epoxide bridging isooctane phenyl porphyrin metal Zn complexs | 桂林理工大学 | 2017-08-04 | — | — | CN | disclosed |