Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 2/20 | 0.67 |
| ▸ | USP7 | Q93009 | 1/20 | 0.67 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20979 | 0.84 | USP8 (0.92) | USP8USP7BCL2MCL1TTR | |
| Anthraquinone SCHEMBL28180729 | 0.84 | USP8 (0.92) | USP8USP7BCL2MCL1TTR | |
| SCHEMBL5075380 | 0.82 | USP8 (0.88) | USP8USP7BCL2MCL1TTR | |
| Anthraquinone SCHEMBL27890701 | 0.82 | MEN1 (0.57) | BCL2MCL1TTRHTR7HTR2B | |
| SCHEMBL28169694 | 0.78 | BCL2 (0.47) | BCL2MCL1TTRHTR7HTR2B | |
| SCHEMBL17105943 | 0.75 | USP8 (0.69) | USP8USP7BCL2MCL1ALDH1A1 | |
| SCHEMBL15271277 | 0.74 | USP7 (0.71) | USP8USP7BCL2MCL1ALDH1A1 | |
| SCHEMBL23968840 | 0.72 | USP7 (0.75) | USP8USP7BCL2MCL1ALDH1A1 | |
| SCHEMBL27326759 | 0.72 | BCAT2 (0.43) | HTR7HTR2BALDH1A1NPC1RAB9A | |
| Anthraquinone SCHEMBL27537802 | 0.70 | MEN1 (0.71) | USP8USP7BCL2MCL1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481722-B | Preparation method of 1, 4-diamino-2, 3-dicyanoanthraquinone | 江苏亚邦染料股份有限公司 | 2017-08-25 | — | — | CN | claimed |
| CN-105481722-B | Preparation method of 1, 4-diamino-2, 3-dicyanoanthraquinone | 江苏亚邦染料股份有限公司 | 2017-08-25 | — | — | CN | disclosed |