Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28139265 | 0.79 | KLKB1 (0.53) | MEN1KMT2AKLKB1GAAHSD17B10 | |
| SCHEMBL3584847 | 0.79 | HDAC1 (0.70) | HTTHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL7081878 | 0.79 | HTT (0.75) | HTTHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL3433732 | 0.78 | GAA (0.59) | HTTHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL16881287 | 0.73 | HTT (0.62) | HTTHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL15142218 | 0.73 | HTT (0.62) | HTTHDAC1HDAC6KLKB1NOS3 | |
| SCHEMBL27785911 | 0.73 | PTGER1 (0.48) | HTTHDAC1MEN1KMT2ATSHR | |
| SCHEMBL28847838 | 0.72 | HDAC1 (0.49) | HDAC1HDAC6MEN1KMT2AGAA | |
| SCHEMBL12321326 | 0.72 | MAPT (0.60) | HTTHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL28205957 | 0.72 | CYP11B1 (0.49) | HTTHDAC1HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074814-A | Glucose transport inhibitor | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |