Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 13/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28139274 | 0.90 | HSD17B10 (0.51) | KLKB1HSD17B10LMNAMAPTPOLB | |
| SCHEMBL553565 | 0.80 | HSD17B10 (0.59) | KLKB1HSD17B10LMNAPOLBTDP1 | |
| SCHEMBL1979091 | 0.80 | MAPT (0.65) | KLKB1HSD17B10LMNAMAPTL3MBTL1 | |
| SCHEMBL28170055 | 0.79 | HTT (0.60) | KLKB1HSD17B10MAPTGAAMEN1 | |
| SCHEMBL28825241 | 0.75 | KLKB1 (0.59) | KLKB1 | |
| SCHEMBL12598742 | 0.74 | MAPT (0.56) | KLKB1LMNAMAPTTDP1L3MBTL1 | |
| SCHEMBL948453 | 0.74 | HSD17B10 (0.61) | KLKB1HSD17B10LMNAMAPTPOLB | |
| SCHEMBL27259482 | 0.74 | KLKB1 (0.51) | KLKB1HSD17B10LMNAMAPTPOLB | |
| Hydrochloric Acid SCHEMBL20258138 | 0.74 | HSD17B10 (0.51) | KLKB1HSD17B10LMNAMAPTPOLB | |
| SCHEMBL28104867 | 0.73 | KLKB1 (0.40) | KLKB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074814-A | Glucose transport inhibitor | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106687455-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2017-05-17 | — | — | CN | disclosed |