Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904567 | 0.86 | DDB1 (0.47) | DDB1CRBNKDM4EHSD17B10GBA1 | |
| SCHEMBL2509278 | 0.73 | KDM4E (0.42) | DDB1CRBNKDM4EIDH1MAPT | |
| SCHEMBL6888144 | 0.73 | HTR3A (0.55) | GAA | |
| SCHEMBL15630464 | 0.73 | ALB (0.46) | KDM4EALDH1A1HPGDNPSR1KMT2A | |
| SCHEMBL6886652 | 0.73 | HTR3A (0.55) | GAA | |
| SCHEMBL17048284 | 0.71 | KDM4E (0.37) | DDB1CRBNKDM4EMAPTGAA | |
| SCHEMBL31472197 | 0.70 | GAA (0.43) | MAP4K4KDM4EHSD17B10GBA1KMT2A | |
| SCHEMBL27638728 | 0.68 | KDM4E (0.58) | KDM4EHSD17B10GBA1ALDH1A1KMT2A | |
| SCHEMBL2507487 | 0.67 | MAPT (0.44) | ALDH1A1NPSR1KMT2ANPC1RAB9A | |
| SCHEMBL2778937 | 0.67 | PTGES2 (0.44) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106983749-A | Androgen receptor modifier and application thereof | 亚拉冈制药公司 | 2017-07-28 | — | — | CN | disclosed |