Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16983062 | 0.97 | DNM1 (0.50) | DNM1TSHRTHRBMGLLCA12 | |
| SCHEMBL15277763 | 0.97 | DNM1 (0.50) | DNM1TSHRTHRBMGLLCA12 | |
| SCHEMBL19159086 | 0.97 | DNM1 (0.50) | DNM1TSHRTHRBMGLLCA12 | |
| Bromide SCHEMBL28182125 | 0.89 | DNM1 (0.57) | DNM1TSHRTHRBMGLLCA12 | |
| SCHEMBL28875521 | 0.86 | DNM1 (0.55) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL8368036 | 0.86 | — | — | |
| SCHEMBL15277761 | 0.86 | DNM1 (0.55) | DNM1TSHRTHRBCA12CA1 | |
| Hydrochloric Acid SCHEMBL27503347 | 0.83 | DNM1 (0.57) | DNM1TSHRTHRBMGLLCA12 | |
| Hydrochloric Acid SCHEMBL27503710 | 0.83 | DNM1 (0.57) | DNM1TSHRTHRBMGLLCA12 | |
| SCHEMBL11479627 | 0.83 | DNM1 (0.50) | DNM1TSHRTHRBMGLLCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107105737-A | Gel capsules comprising plant cells | 卡普苏姆公司 | 2017-08-29 | — | — | CN | disclosed |