SCHEMBL28173303

SCHEMBL28173303

O=S(=O)(O)c1c(-c2ccc3ccccc3c2)cccc1-c1ccc2ccccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.53
HDAC4 P56524 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
ESR2 Q92731 2/20 0.44
ESR1 P03372 1/20 0.44
MAOB P27338 1/20 0.43
ALOX5 P09917 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23432940 0.88 GSTP1 (0.52) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL9507935 0.82 GSTP1 (0.53) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL29143202 0.80 SLC6A2 (0.41) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL21794264 0.77 TSHR (0.46) HDAC4HDAC2HDAC8TSHRPTGS2
SCHEMBL30491158 0.76 GSTP1 (0.70) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL28508645 0.76 GSTP1 (0.70) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL29006818 0.76 HDAC4 (0.46) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL598168 0.75 HDAC4 (0.72) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL30335758 0.75 HDAC4 (0.72) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL3176171 0.74 GSTP1 (0.61) GSTP1HDAC4HDAC2HDAC8SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107188781-A A kind of method that isopulegol is prepared by citronellal 万华化学集团股份有限公司 2017-09-22 CN disclosed