Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16733218 | 0.70 | — | — | |
| SCHEMBL9410125 | 0.70 | — | — | |
| SCHEMBL11467959 | 0.69 | — | — | |
| SCHEMBL11473927 | 0.67 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL11473923 | 0.67 | ALDH1A1 (0.43) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11474592 | 0.67 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL27154278 | 0.67 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL209649 | 0.65 | — | — | |
| SCHEMBL9298738 | 0.65 | — | — | |
| SCHEMBL16732357 | 0.65 | TDP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207467-A | 2, 4-dioxo-quinazoline-6-sulfonamide derivatives as inhibitors of PARG | 癌症研究科技有限公司 | 2017-09-26 | — | — | CN | claimed |
| CN-107207467-A | 2, 4-dioxo-quinazoline-6-sulfonamide derivatives as inhibitors of PARG | 癌症研究科技有限公司 | 2017-09-26 | — | — | CN | disclosed |