Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20749484 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1TDP1LMNACA12 | |
| SCHEMBL668838 | 0.85 | KDM4E (0.69) | KDM4EALDH1A1TDP1LMNACA12 | |
| SCHEMBL28175165 | 0.85 | KDM4E (0.71) | KDM4EALDH1A1TDP1LMNACA12 | |
| SCHEMBL1423804 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1TDP1LMNACA12 | |
| SCHEMBL16369830 | 0.81 | TSHR (0.50) | KDM4EALDH1A1TDP1LMNACA12 | |
| Hydrochloric Acid SCHEMBL1424857 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1TDP1LMNACA12 | |
| SCHEMBL2671214 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1TDP1LMNACA12 | |
| SCHEMBL17544740 | 0.79 | CA12 (0.41) | KDM4EALDH1A1TDP1LMNACA12 | |
| SCHEMBL8235386 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1TDP1LMNACA12 | |
| SCHEMBL4874263 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1TDP1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074807-A | Compositions and methods for inhibiting histone demethylase | 吉利德科学公司 | 2017-08-18 | — | — | CN | disclosed |