Glutathione

Glutathione

SCHEMBL28175255

NC(CCC(=O)NC(CS)C(=O)NCC(=O)O)C(=O)O.NC(CSSCC(N)C(=O)O)C(=O)O

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.85
GSTK1 Q9Y2Q3 1/20 0.85
GLO1 Q04760 3/20 0.58
FNTA P49354 2/20 0.42
FNTB P49356 2/20 0.42
PGGT1B P53609 1/20 0.42
NOD1 Q9Y239 4/20 0.41
FOLH1 Q04609 2/20 0.39
GRM8 O00222 1/20 0.37
GRM6 O15303 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GSR P00390 1/20 0.37
CYP1A2 P05177 1/20 0.37
GRIK1 P39086 1/20 0.37
GRM5 P41594 1/20 0.37
GRIA1 P42261 1/20 0.37
GRIA2 P42262 1/20 0.37
GRIA3 P42263 1/20 0.37
SLC1A3 P43003 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutathione SCHEMBL16513351 1.00 PTGS1 (0.85) PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL16513349 1.00 PTGS1 (0.85) PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL28175253 1.00 PTGS1 (0.85) PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL26121838 0.95 PTGS1 (0.78) PTGS1GSTK1GLO1FNTAFNTB
Oxiglutatione SCHEMBL27983949 0.95 PTGS1 (0.85) PTGS1GSTK1GLO1FNTAFNTB
Oxiglutatione SCHEMBL10537467 0.95 PTGS1 (0.85) PTGS1GSTK1GLO1FNTAFNTB
Oxiglutatione SCHEMBL20898434 0.93 PTGS1 (0.81) PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL724436 0.93 PTGS1 (0.85) PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL722499 0.93 PTGS1 (0.85) PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL722500 0.93 PTGS1 (0.85) PTGS1GSTK1GLO1FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107106540-A Composition for preventing or treating obesity comprising alpha-lipoic acid and N-acetylcysteine as active ingredients 财团法人峨山社会福利财团 2017-08-29 CN disclosed