Glutathione

Glutathione

SCHEMBL722500

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nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.85
GSTK1 Q9Y2Q3 1/20 0.85
GLO1 Q04760 3/20 0.58
NOD1 Q9Y239 4/20 0.41
FNTA P49354 2/20 0.40
FNTB P49356 2/20 0.40
PGGT1B P53609 1/20 0.40
FOLH1 Q04609 2/20 0.39
GRM8 O00222 1/20 0.37
GRM6 O15303 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GSR P00390 1/20 0.37
CYP1A2 P05177 1/20 0.37
GRIK1 P39086 1/20 0.37
GRM5 P41594 1/20 0.37
GRIA1 P42261 1/20 0.37
GRIA2 P42262 1/20 0.37
GRIA3 P42263 1/20 0.37
SLC1A3 P43003 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutathione SCHEMBL722499 1.00 PTGS1 (0.85) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL724436 1.00 PTGS1 (0.85) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL16513637 0.94 PTGS1 (0.80) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL16513640 0.94 PTGS1 (0.80) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL16513351 0.93 PTGS1 (0.85) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL28175253 0.93 PTGS1 (0.85) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL16513349 0.93 PTGS1 (0.85) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL28175255 0.93 PTGS1 (0.85) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL1105665 0.92 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL5167030 0.92 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130209366-A1 Glutathione-Lanthionine Compounds and Methods Related Thereto OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 2013-08-15 US claimed
EP-3169698-B1 NOVEL COMPOUNDS THE PROVOST FELLOWS FOUND SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF HOLY AND UNDIV TRI (IE) 2018-12-05 EP disclosed
US-20130209366-A1 Glutathione-Lanthionine Compounds and Methods Related Thereto OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 2013-08-15 US disclosed
US-20130209366-A1 Glutathione-Lanthionine Compounds and Methods Related Thereto OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 2013-08-15 US disclosed
WO-2012027455-A1 GLUTATHIONE-LANTHIONINE COMPOUNDS AND METHODS RELATED THERETO THE UNIVERSITY OF TOLEDO (US) 2012-03-01 WO disclosed
WO-2012027455-A1 GLUTATHIONE-LANTHIONINE COMPOUNDS AND METHODS RELATED THERETO THE UNIVERSITY OF TOLEDO (US) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130209366-A1 Glutathione-Lanthionine Compounds and Methods Related Thereto GPX1, GCLC, GSS PTGS1 114/4885GSTK1 12/4885GLO1 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.