Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19500852 | 0.84 | CYP3A4 (0.39) | ARTRPV4KDM4EALDH1A1GLA | |
| SCHEMBL4402110 | 0.78 | AR (0.51) | ARPGR | |
| SCHEMBL28176921 | 0.76 | SLC6A2 (0.37) | ARTRPV4 | |
| SCHEMBL12367734 | 0.75 | NOTUM (0.40) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2814890 | 0.75 | GAA (0.50) | ARKDM4EALDH1A1GLAGAA | |
| SCHEMBL4474145 | 0.75 | KDM1A (0.39) | ARPGRKIF11MAP3K12 | |
| SCHEMBL4573376 | 0.75 | AR (0.43) | ARTRPV4KDM4EALDH1A1GLA | |
| SCHEMBL28176915 | 0.72 | AR (0.33) | AR | |
| SCHEMBL2814868 | 0.72 | PDE7A (0.44) | ARALDH1A1KIF11 | |
| SCHEMBL3919628 | 0.71 | AR (0.43) | ARALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107250110-A | The noval chemical compound of (RET) inhibitor is reset as transfection | 葛兰素史克知识产权发展有限公司 | 2017-10-13 | — | — | CN | disclosed |