Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19461387 | 0.79 | NR1H2 (0.48) | SLC6A2SLC6A4RXRARXRBRXRG | |
| SCHEMBL28175925 | 0.77 | KDM4E (0.38) | RXRARXRBRXRGARPOLQ | |
| SCHEMBL28175966 | 0.76 | AR (0.36) | TRPV4AR | |
| SCHEMBL17593408 | 0.75 | PDE7A (0.43) | SLC6A2SLC6A4AR | |
| SCHEMBL28155357 | 0.75 | SIRT2 (0.39) | RXRARXRBRXRGPOLQ | |
| SCHEMBL19073460 | 0.73 | IDO1 (0.34) | POLQ | |
| SCHEMBL4402110 | 0.70 | AR (0.51) | RXRARXRBRXRGAR | |
| SCHEMBL28176917 | 0.70 | RXRA (0.44) | RXRARXRBRXRGPOLQ | |
| SCHEMBL14549279 | 0.69 | IDO1 (0.34) | — | |
| SCHEMBL28175906 | 0.68 | FFAR4 (0.43) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107250110-A | The noval chemical compound of (RET) inhibitor is reset as transfection | 葛兰素史克知识产权发展有限公司 | 2017-10-13 | — | — | CN | disclosed |