Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975254 | 1.00 | USP2 (0.47) | USP2CYP3A4SMN1; SMN2THRBPTPN1 | |
| SCHEMBL8911882 | 0.97 | THRB (0.48) | USP2CYP3A4SMN1; SMN2THRBPTPN1 | |
| SCHEMBL11281475 | 0.95 | USP2 (0.50) | USP2CYP3A4SMN1; SMN2THRBPTPN1 | |
| SCHEMBL16074800 | 0.89 | THRB (0.50) | THRBPTPN1PSMD14PLA2G1BMMP2 | |
| SCHEMBL16074836 | 0.89 | THRB (0.50) | THRBPTPN1PSMD14PLA2G1BMMP2 | |
| SCHEMBL16074890 | 0.89 | THRB (0.50) | THRBPTPN1PSMD14PLA2G1BMMP2 | |
| SCHEMBL16074963 | 0.89 | THRB (0.50) | THRBPTPN1PSMD14PLA2G1BMMP2 | |
| SCHEMBL16074844 | 0.89 | THRB (0.50) | THRBPTPN1PSMD14PLA2G1BMMP2 | |
| SCHEMBL16074721 | 0.89 | THRB (0.50) | THRBPTPN1PSMD14PLA2G1BMMP2 | |
| SCHEMBL16074802 | 0.89 | THRB (0.50) | THRBPTPN1PSMD14PLA2G1BMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100243154-A1 | Cured In Place Pipe Liner With Styrene Barrier | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| US-7033458-B2 | Process for improving interfacial adhesion in a laminate | NIKE, INC. (US) | 2006-04-25 | — | — | US | disclosed |
| US-20020187289-A1 | Process for improving interfacial adhesion in a laminate | NIKE INTERNATIONAL, LTD. | 2002-12-12 | — | — | US | disclosed |