Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336866 | 0.81 | KMT2A (0.36) | KMT2AMEN1MAPK1HTTCYP3A4 | |
| SCHEMBL24565293 | 0.81 | F10 (0.38) | KMT2AMEN1MAPK1HTTCYP3A4 | |
| SCHEMBL28278368 | 0.81 | MAPT (0.45) | KMT2AMEN1CYP3A4NPSR1ALDH1A1 | |
| SCHEMBL19419830 | 0.80 | CYP3A4 (0.38) | KMT2AMEN1MAPK1HTTCYP3A4 | |
| SCHEMBL24565300 | 0.80 | CYP3A4 (0.38) | KMT2AMEN1MAPK1HTTCYP3A4 | |
| SCHEMBL9550831 | 0.79 | KMT2A (0.35) | KMT2AMEN1MAPK1HTTCYP3A4 | |
| SCHEMBL24565313 | 0.76 | LMNA (0.34) | KMT2AMEN1MAPK1HTTCYP3A4 | |
| SCHEMBL24565349 | 0.76 | F10 (0.39) | KMT2AMEN1MAPK1HTTLMNA | |
| SCHEMBL7328219 | 0.76 | F10 (0.39) | KMT2AMEN1MAPK1HTTLMNA | |
| SCHEMBL28723335 | 0.76 | KDM4E (0.36) | KMT2AMEN1LMNATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105517574-B | The combination product of hepatitis C virus inhibitors | 百时美施贵宝公司 | 2019-01-18 | — | — | CN | disclosed |
| CN-104302290-B | Hepatitis c virus inhibitors | 百时美施贵宝公司 | 2017-10-24 | — | — | CN | disclosed |