Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 11/20 | 0.80 |
| ▸ | MAPT | P10636 | 11/20 | 0.80 |
| ▸ | BACE1 | P56817 | 9/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.80 |
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.80 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.80 |
| ▸ | MAOA | P21397 | 2/20 | 0.80 |
| ▸ | MAOB | P27338 | 2/20 | 0.80 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.80 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.80 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.80 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.80 |
| ▸ | MMP9 | P14780 | 2/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3218050 | 1.00 | APP (0.80) | APPMAPTBACE1CYP2D6CYP2C9 | |
| Curcumin SCHEMBL28150920 | 0.93 | APP (0.76) | APPMAPTBACE1CYP2D6CYP2C9 | |
| SCHEMBL3211860 | 0.92 | APP (0.82) | APPMAPTBACE1CYP2D6CYP2C9 | |
| SCHEMBL3211843 | 0.92 | APP (0.82) | APPMAPTBACE1CYP2D6CYP2C9 | |
| SCHEMBL3207803 | 0.90 | MAPT (0.86) | APPMAPTBACE1CYP2D6CYP2C9 | |
| SCHEMBL3207789 | 0.90 | MAPT (0.86) | APPMAPTBACE1CYP2D6CYP2C9 | |
| SCHEMBL3214032 | 0.90 | BACE1 (0.80) | APPMAPTBACE1CYP2D6CYP2C9 | |
| SCHEMBL3214044 | 0.90 | BACE1 (0.80) | APPMAPTBACE1CYP2D6CYP2C9 | |
| Curcumin SCHEMBL28282502 | 0.89 | APP (0.94) | APPMAPTBACE1CYP2D6CYP2C9 | |
| Curcumin SCHEMBL17629818 | 0.89 | APP (1.00) | APPMAPTBACE1CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189543-A1 | Compositions and methods for the treatment of leukemia | QUIGLEY CORPORATION, THE | 2006-08-24 | — | — | US | claimed |
| US-20240165191-A1 | COMPOSITIONS AND METHODS FOR REDUCING THE TRANSMISSIVITY OF ILLNESSES USING AN ORAL DELIVERY SYSTEM | LORENZEN LEE H (US) | 2024-05-23 | — | — | US | disclosed |
| US-20220080020-A1 | COMPOSITIONS AND METHODS FOR REDUCING THE TRANSMISSIVITY OF ILLNESSES USING AN ORAL DELIVERY SYSTEM | MONTAGNIER LUC (US) | 2022-03-17 | — | — | US | disclosed |
| WO-2022046668-A1 | COMPOSITIONS AND METHODS FOR REDUCING THE TRANSMISSIVITY OF ILLNESSES | MONTAGNIER LUC (US) | 2022-03-03 | — | — | WO | disclosed |
| CN-114007427-A | Egg replacer and compositions comprising the same and methods of producing the same | 完美日股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-114007433-A | Recombinant milk proteins and compositions comprising the same | 完美日股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| WO-2020079608-A1 | CHOCOLATE MATRIX COMPRISING CURCUMIN AND RESVERATROL | E.N.S. - EUROPEAN NUTRITIONAL SUPPLEMENTS S.R.L. (IT) | 2020-04-23 | — | — | WO | disclosed |
| US-9211270-B2 | Method for improving the efficacy of curcuminoids and their analogs | ASAC Compañia de Technologia e Invertigación, S.A. (ES) | 2015-12-15 | — | — | US | disclosed |
| US-8962674-B2 | Curcumin derivative | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20140257170-A1 | Method for Improving the Efficacy of Curcuminoids and Their Analogs | ASAC Compañía de Biotecnología e Investigación, S.A. (ES) | 2014-09-11 | — | — | US | disclosed |
| US-20030105031-A1 | Methods for the treatment of skin disorders | QUIGLEY CORPORATION, THE | 2003-06-05 | — | — | US | disclosed |
| US-20030099730-A1 | Nutritional supplement and methods of using it | QUIGLEY CORPORATION, THE | 2003-05-29 | — | — | US | disclosed |
| WO-2003013428-A2 | NUTRITIONAL SUPPLEMENTS AND METHODS OF USING SAME | THE QUIGLEY CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |
| US-20030031737-A1 | Medicinal composition and method of using it | QUIGLEY CORPORATION, THE | 2003-02-13 | — | — | US | disclosed |
| EP-0839037-A4 | BIOPROTECTANT COMPOSITION, METHOD OF USE AND EXTRACTION PROCESS OF CURCUMINOIDS | SABINSA CORP (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0839037-A1 | BIOPROTECTANT COMPOSITION, METHOD OF USE AND EXTRACTION PROCESS OF CURCUMINOIDS | Sabinsa Corporation (US) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003674-A1 | BIOPROTECTANT COMPOSITION, METHOD OF USE AND EXTRACTION PROCESS OF CURCUMINOIDS | SABINSA CORPORATION (US) | 1997-02-06 | — | — | WO | disclosed |
| EP-0440885-B1 | Combinations of compounds isolated from curcuma SPP as anti-inflammatory agents | PT DARIA VARIA LAB (ID) | 1994-04-06 | — | — | EP | disclosed |
| US-5120538-A | Turmeric herb extracted oil free of bis-desmethoxycurcumin | PT DARYA-VARIA LABORATORIA (ID) | 1992-06-09 | — | — | US | disclosed |
| EP-0440885-A1 | Combinations of compounds isolated from curcuma SPP as anti-inflammatory agents | PT DARYA-VARIA LABORATORIA (ID) | 1991-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105031-A1 | Methods for the treatment of skin disorders | TYR, CUTA, NFATC1 | APP 1343/4885MAPT 1999/4885BACE1 1705/4885 |
| US-20060189543-A1 | Compositions and methods for the treatment of leukemia | MCL1, IL2, MYADM | APP 4545/4885MAPT 4618/4885BACE1 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.