SCHEMBL28178477

SCHEMBL28178477

Nc1cccn1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4565293 0.67
SCHEMBL28284430 0.65
SCHEMBL8486835 0.65
SCHEMBL26596870 0.60 HPGD (0.32)
SCHEMBL15326678 0.58 PTPN1 (0.35)
SCHEMBL4414820 0.58 MKNK1 (0.39)
SCHEMBL27551614 0.58
SCHEMBL27869260 0.51
SCHEMBL4917339 0.49
SCHEMBL28230063 0.48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796439-A A kind of hydroxyproline class peptide derivant and its preparation method and application 西安交通大学 2019-05-24 CN claimed
CN-107814765-A The preparation method of 2 (pyridylazo of 3,5 dibromo 2) 5 diethylaminophenols 天津市化学试剂研究所有限公司 2018-03-20 CN claimed
CN-107814762-A The preparation method of 4 (pyridylazo of 3,5 dibromo 2) 1,3 diaminobenzenes 天津市化学试剂研究所有限公司 2018-03-20 CN claimed
CN-109824582-A A kind of alanine derivatives and its preparation method and application 西安交通大学 2019-05-31 CN disclosed
CN-105503731-B 1- (2,6- dichlor-4-trifluoromethyls) phenyl -3- cyano group -5- methylenes amino-pyrazol type compound and its micro-wave digestion synthetic method and application 中南民族大学 2018-05-15 CN disclosed
CN-107428750-A TRIAZOLOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF 豪夫迈·罗氏有限公司 2017-12-01 CN disclosed
CN-107266438-A A kind of heterocyclic organic electroluminescent compounds and its organic electroluminescence device 上海道亦化工科技有限公司 2017-10-20 CN disclosed