Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140854 | 0.83 | ATM (0.48) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL28289189 | 0.81 | NOTUM (0.41) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL29264051 | 0.77 | SLC6A4 (0.37) | RAB9AALDH1A1NPC1 | |
| SCHEMBL76912 | 0.73 | SMN1; SMN2 (0.52) | MKNK1MKNK2GAARAB9ASMN1; SMN2 | |
| SCHEMBL27881807 | 0.73 | ALDH1A1 (0.41) | MKNK1MKNK2MAPTKMT2ALMNA | |
| SCHEMBL15058294 | 0.71 | POLB (0.50) | SMN1; SMN2HTTPOLBRECQLL3MBTL1 | |
| SCHEMBL3834300 | 0.71 | ALDH1A1 (0.40) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL6105687 | 0.71 | RAB9A (0.45) | MKNK1MKNK2MAPTKMT2AMEN1 | |
| SCHEMBL3081572 | 0.67 | MKNK1 (0.41) | MKNK1MKNK2MAPTKMT2AMEN1 | |
| SCHEMBL296099 | 0.67 | MAPT (0.56) | MAPTKMT2AMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8262881-B2 | Method for finger-printing heparins | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2012-09-11 | — | — | US | disclosed |
| US-20110048946-A1 | METHOD FOR FINGER-PRINTING HEPARINS | VIRGINIA COMMONWEALTH UNIVERSITY | 2011-03-03 | — | — | US | disclosed |
| WO-2009108845-A2 | METHOD FOR FINGER-PRINTING HEPARINS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2009-09-03 | — | — | WO | disclosed |