SCHEMBL28180147

SCHEMBL28180147

CCCCc1cc2[nH]nnc2c(N)c1CCCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 3/20 0.33
NOS2 P35228 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32
GABRA4 P48169 1/20 0.32
GABRE P78334 1/20 0.32
GABRA6 Q16445 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5465512 0.85 TLR8 (0.33) TLR8NOS2NPC1RAB9ATP53
SCHEMBL10884468 0.84 HCAR3 (0.31) TLR8HCAR3HCAR2
SCHEMBL5450709 0.84 TLR8 (0.33) TLR8NPC1RAB9ATP53TSHR
SCHEMBL5455695 0.81 TLR8 (0.35) TLR8HPGD
SCHEMBL5459879 0.80 TLR8 (0.34) TLR8TP53TSHRHPGDHTT
SCHEMBL5449224 0.80 TLR8 (0.34) TLR8TP53TSHRHPGDHTT
SCHEMBL5450965 0.80 TLR8 (0.34) TLR8TP53TSHRHPGDHTT
SCHEMBL5447126 0.80 TLR8 (0.34) TLR8TP53TSHRHPGDHTT
SCHEMBL5455650 0.80 TLR8 (0.34) TLR8TP53TSHRHPGDHTT
SCHEMBL5460077 0.80 TLR8 (0.34) TLR8TP53TSHRHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104845712-B A kind of high-performance antiwear hydraulic oil and preparation method thereof 苏州赛斯德工程设备有限公司 2018-03-27 CN claimed
CN-107760418-A A kind of ashless antiwear hydraulic lubricant oil composition and preparation method thereof 中国科学院宁波材料技术与工程研究所 2018-03-06 CN claimed
CN-107353979-A A kind of preparation method of hydraulic oil for plant equipment 合肥嘉仕诚能源科技有限公司 2017-11-17 CN claimed
CN-109097154-A A kind of hydraulic transmission oil and its production method 江苏司能润滑科技有限公司 2018-12-28 CN disclosed
CN-104845712-B A kind of high-performance antiwear hydraulic oil and preparation method thereof 苏州赛斯德工程设备有限公司 2018-03-27 CN disclosed
CN-107760418-A A kind of ashless antiwear hydraulic lubricant oil composition and preparation method thereof 中国科学院宁波材料技术与工程研究所 2018-03-06 CN disclosed
CN-107353979-A A kind of preparation method of hydraulic oil for plant equipment 合肥嘉仕诚能源科技有限公司 2017-11-17 CN disclosed