Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16543124 | 0.77 | GPR84 (0.39) | JAK2THRBGPR84CDK1CDK4 | |
| SCHEMBL22783664 | 0.74 | JAK2 (0.61) | JAK2THRBDHODHLMNAALDH1A1 | |
| SCHEMBL25391975 | 0.71 | JAK2 (0.59) | JAK2THRBMEN1KMT2ADHODH | |
| SCHEMBL10962665 | 0.71 | JAK2 (0.59) | JAK2THRBDHODHLMNAALDH1A1 | |
| SCHEMBL26988788 | 0.71 | JAK2 (0.41) | JAK2THRBMEN1KMT2AGLA | |
| SCHEMBL26989603 | 0.71 | JAK2 (0.41) | JAK2THRBMEN1KMT2AGLA | |
| SCHEMBL122310 | 0.70 | JAK2 (0.57) | JAK2THRBDHODH | |
| SCHEMBL9715507 | 0.70 | JAK2 (1.00) | JAK2THRBDHODHLMNAALDH1A1 | |
| SCHEMBL44527 | 0.70 | JAK2 (1.00) | JAK2THRBDHODHLMNAALDH1A1 | |
| SCHEMBL11130450 | 0.70 | JAK2 (0.57) | JAK2THRBDHODHLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266374-A | A kind of monokaryon zinc super molecular complex and preparation method thereof | 宁波大学 | 2017-10-20 | — | — | CN | disclosed |