Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.55 |
| ▸ | WNT3A | P56704 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469811 | 0.80 | MEN1 (0.70) | MEN1KMT2ACTNNB1WNT3ANPC1 | |
| SCHEMBL28182768 | 0.79 | CTNNB1 (0.49) | MEN1KMT2ACTNNB1WNT3ANPC1 | |
| SCHEMBL2237626 | 0.77 | MEN1 (0.76) | MEN1KMT2ACTNNB1WNT3ANPC1 | |
| SCHEMBL29458253 | 0.77 | MEN1 (0.76) | MEN1KMT2ACTNNB1WNT3ANPC1 | |
| SCHEMBL6486626 | 0.76 | CTNNB1 (0.66) | MEN1KMT2ACTNNB1WNT3AALDH1A1 | |
| SCHEMBL4865452 | 0.76 | CTNNB1 (0.66) | MEN1KMT2ACTNNB1WNT3AALDH1A1 | |
| SCHEMBL1092123 | 0.74 | ATM (0.81) | MEN1KMT2ACTNNB1WNT3AALDH1A1 | |
| SCHEMBL13785040 | 0.74 | CTNNB1 (0.64) | MEN1KMT2ACTNNB1WNT3AALDH1A1 | |
| SCHEMBL2843731 | 0.74 | CTNNB1 (0.64) | MEN1KMT2ACTNNB1WNT3AALDH1A1 | |
| SCHEMBL4258312 | 0.74 | CTNNB1 (0.64) | MEN1KMT2ACTNNB1WNT3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107383024-B | The class compound of fused tricyclic containing imidazoles and its application | 广州必贝特医药技术有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107383024-A | The class compound of fused tricyclic containing imidazoles and its application | 广州必贝特医药技术有限公司 | 2017-11-24 | — | — | CN | disclosed |