Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.49 |
| ▸ | WNT3A | P56704 | 7/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182766 | 0.90 | CTNNB1 (0.50) | CTNNB1WNT3APRKCITAS1R3TAS1R1 | |
| SCHEMBL28182793 | 0.79 | MEN1 (0.57) | CTNNB1WNT3ARAB9ANPC1MEN1 | |
| SCHEMBL14044259 | 0.78 | PRKCI (0.58) | CTNNB1WNT3APRKCITAS1R3TAS1R1 | |
| SCHEMBL1182701 | 0.77 | PRKCI (0.57) | CTNNB1WNT3APRKCITAS1R3TAS1R1 | |
| SCHEMBL6181845 | 0.77 | PRKCI (0.57) | CTNNB1WNT3APRKCITAS1R3TAS1R1 | |
| SCHEMBL1091802 | 0.77 | ATM (0.69) | CTNNB1WNT3APRKCITAS1R3TAS1R1 | |
| SCHEMBL28182836 | 0.76 | CTNNB1 (0.37) | CTNNB1WNT3ATAS1R3TAS1R1HDAC3 | |
| SCHEMBL13516241 | 0.75 | MEN1 (0.63) | CTNNB1WNT3APRKCITAS1R3TAS1R1 | |
| SCHEMBL15088740 | 0.74 | CTNNB1 (0.60) | CTNNB1WNT3APRKCITAS1R3TAS1R1 | |
| SCHEMBL11022828 | 0.74 | HPGD (0.70) | CTNNB1WNT3APRKCITAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107383024-B | The class compound of fused tricyclic containing imidazoles and its application | 广州必贝特医药技术有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107383024-A | The class compound of fused tricyclic containing imidazoles and its application | 广州必贝特医药技术有限公司 | 2017-11-24 | — | — | CN | disclosed |