Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.50 |
| ▸ | ADRB1 known ✓ | P08588 | 3/20 | 0.49 |
| ▸ | DRD3 known ✓ | P35462 | 2/20 | 0.49 |
| ▸ | DRD2 known ✓ | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 known ✓ | P21917 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | BLM | P54132 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL27771961 | 0.89 | TDP1 (0.55) | TDP1KDM4EMAPTBLMLMNA | |
| Acetic Acid SCHEMBL28397274 | 0.86 | TDP1 (0.55) | TDP1KDM4EMAPTBLMLMNA | |
| SCHEMBL29525823 | 0.84 | TDP1 (0.65) | TDP1KDM4EMAPTBLMLMNA | |
| SCHEMBL241136 | 0.84 | TDP1 (0.65) | TDP1KDM4EMAPTBLMLMNA | |
| Racepinephrine SCHEMBL11414997 | 0.80 | TDP1 (0.79) | TDP1KDM4EMAPTBLMLMNA | |
| Epinephrine SCHEMBL11414992 | 0.80 | TDP1 (0.79) | TDP1KDM4EMAPTBLMLMNA | |
| Methylamine SCHEMBL5553020 | 0.80 | TDP1 (0.67) | TDP1KDM4EMAPTBLMLMNA | |
| Formic Acid SCHEMBL29183960 | 0.79 | TDP1 (0.55) | TDP1KDM4EMAPTBLMLMNA | |
| Isopropylamine SCHEMBL10604489 | 0.78 | TDP1 (0.70) | TDP1KDM4EMAPTBLMLMNA | |
| SCHEMBL21348210 | 0.78 | FFAR1 (0.51) | TDP1KDM4EMAPTBLMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382728-A | 2 (3,4 dihydroxy phenyl) ethanol succinates and its extracting method and application | 大理大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-107382728-A | 2 (3,4 dihydroxy phenyl) ethanol succinates and its extracting method and application | 大理大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-107382728-A | 2 (3,4 dihydroxy phenyl) ethanol succinates and its extracting method and application | 大理大学 | 2017-11-24 | — | — | CN | disclosed |