Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.47 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetaldehyde SCHEMBL27752382 | 0.88 | KDM1A (0.42) | KDM1AKDM1BHTR2CHTR2BKDM4E | |
| SCHEMBL434606 | 0.87 | KDM1A (0.52) | KDM1AKDM1BHTR2CHTR2BKDM4E | |
| SCHEMBL28710440 | 0.85 | KDM1A (0.40) | KDM1AKDM1BHTR2CHTR2BKDM4E | |
| Formic Acid SCHEMBL27500254 | 0.81 | GAA (0.46) | KDM1AKDM1BKDM4EGAAADRA1D | |
| Acetone SCHEMBL27752381 | 0.80 | DRD4 (0.45) | KDM1AKDM1BKDM4EGAAHCAR2 | |
| SCHEMBL6203314 | 0.79 | TSHR (0.45) | KDM1AKDM1BKDM4EGAAADRA1D | |
| SCHEMBL434672 | 0.79 | KDM4E (0.50) | KDM1AKDM1BHTR2CHTR2BKDM4E | |
| SCHEMBL316350 | 0.79 | KDM4E (0.55) | KDM1AKDM1BHTR2CHTR2BKDM4E | |
| SCHEMBL22321329 | 0.78 | KDM4E (0.46) | KDM1AKDM1BHTR2CHTR2BKDM4E | |
| SCHEMBL22321328 | 0.78 | KDM4E (0.46) | KDM1AKDM1BHTR2CHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431436-B | Pyrrolo [2,3-D ] pyrimidine derivatives, processes for their preparation and their use as kinase inhibitors | 内尔维阿诺医学科学有限公司 | 2017-11-28 | — | — | CN | claimed |