Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | TP53 | P04637 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CASP1 | P29466 | 5/20 | 0.50 |
| ▸ | CASP7 | P55210 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25230489 | 0.84 | CYP1B1 (0.65) | CYP1B1CYP1A1CYP1A2KDM4EMAPT | |
| SCHEMBL25234796 | 0.81 | KDM4E (0.65) | CYP1B1CYP1A1CYP1A2KDM4EMAPT | |
| SCHEMBL1976922 | 0.80 | ABCB1 (0.60) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL1974622 | 0.80 | ABCB1 (0.60) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL1972783 | 0.79 | MAPT (0.61) | CYP1B1CYP1A1CYP1A2KDM4EMAPT | |
| SCHEMBL1977465 | 0.79 | MAPT (0.61) | CYP1B1CYP1A1CYP1A2KDM4EMAPT | |
| SCHEMBL17786509 | 0.77 | CYP1B1 (0.60) | CYP1B1CYP1A1CYP1A2KDM4EMAPT | |
| SCHEMBL28193893 | 0.77 | KDM4E (0.53) | CYP1B1CYP1A1CYP1A2KDM4EMAPT | |
| SCHEMBL25205540 | 0.75 | ACHE (0.66) | CYP1B1CYP1A1CYP1A2KDM4EMAPT | |
| SCHEMBL1421624 | 0.75 | MAPT (0.61) | CYP1B1CYP1A1CYP1A2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573315-A | A kind of flavone compound in hawthorn and preparation method and application | 云南中烟工业有限责任公司 | 2018-01-12 | — | — | CN | disclosed |