Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CALML3 | P27482 | 1/20 | 0.34 |
| ▸ | SDHA | P31040 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942123 | 0.81 | PDK1 (0.39) | PDK1PDK2PDK3LMNANPSR1 | |
| SCHEMBL23866592 | 0.81 | MALT1 (0.46) | LMNAMAOAPTGS1MAOBCALML3 | |
| SCHEMBL553866 | 0.80 | SMN1; SMN2 (0.43) | PDK1PDK2PDK3 | |
| SCHEMBL16058395 | 0.80 | HCRTR2 (0.40) | PDK1PDK2PDK3 | |
| SCHEMBL25267951 | 0.80 | HCRTR2 (0.40) | PDK1PDK2PDK3 | |
| SCHEMBL553865 | 0.80 | SMN1; SMN2 (0.43) | PDK1PDK2PDK3 | |
| SCHEMBL3939060 | 0.79 | XPNPEP1 (0.38) | PDK1PDK2PDK3CA12CA1 | |
| SCHEMBL17893278 | 0.78 | PDK1 (0.42) | PDK1PDK2PDK3CA12CA1 | |
| SCHEMBL5560259 | 0.76 | PDK1 (0.59) | PDK1PDK2PDK3CA12CA1 | |
| SCHEMBL509358 | 0.76 | PDK1 (0.59) | PDK1PDK2PDK3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367482-B | N acyl sulfonamides apoptosis accelerator | 阿斯利康(瑞典)有限公司 | 2017-12-12 | — | — | CN | disclosed |