SCHEMBL28185148

SCHEMBL28185148

CC(=O)C1=CC=CC(C(C)=O)(c2ccccc2)C1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.34
OPRL1 P41146 2/20 0.34
HDAC9 Q9UKV0 1/20 0.34
AKR1C1 Q04828 1/20 0.32
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
HDAC4 P56524 2/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
OPRD1 P41143 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6128103 0.78 AKR1C1 (0.37) HDAC9AKR1C1HDAC4KMT2A
SCHEMBL27486632 0.77 KMT2A (0.33) OPRM1OPRL1HDAC9MAPTMEN1
SCHEMBL1434701 0.75 HDAC9 (0.34) HDAC9AKR1C1MAPTHDAC4
SCHEMBL29094947 0.75 TSHR (0.39) HDAC9AKR1C1MAPTRAB9AMEN1
SCHEMBL31491185 0.74 OPRM1 (0.33) OPRM1OPRL1HDAC9AKR1C1MAPT
SCHEMBL3836530 0.72 HDAC4 (0.39) OPRM1OPRL1HDAC9AKR1C1HDAC4
Acetonitrile SCHEMBL28747283 0.70 CYP11B1 (0.34) OPRM1OPRL1AKR1C1MAPTHDAC4
SCHEMBL28808541 0.69 HDAC9 (0.33) HDAC9AKR1C1
SCHEMBL26932428 0.69
SCHEMBL28794322 0.68 HDAC9 (0.39) OPRM1OPRL1HDAC9AKR1C1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107326393-B A kind of preparation method of water power parsing oxygen non-precious metal catalyst 广西大学 2019-08-23 CN disclosed
CN-107326393-A A kind of water power parses the preparation method of oxygen non-precious metal catalyst 广西大学 2017-11-07 CN disclosed