Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31227217 | 0.84 | PIM2 (0.45) | PIM2PIM1ABL1HDAC3HDAC1 | |
| SCHEMBL16995118 | 0.79 | PIM2 (0.52) | PIM2PIM1NPY5RKMODHODH | |
| SCHEMBL6960490 | 0.79 | NPY5R (0.65) | PIM2PIM1NPY5RKMOPIK3CD | |
| SCHEMBL16291541 | 0.76 | CYP2D6 (0.45) | MKNK1MKNK2PIM2PIM1DHODH | |
| SCHEMBL25326508 | 0.74 | KMO (0.49) | NPY5RKMOP2RX7PIK3CDPIK3CA | |
| SCHEMBL12492145 | 0.74 | CYP3A4 (0.52) | PIM2PIM1NPY5RKMOHDAC3 | |
| SCHEMBL23535785 | 0.73 | PIM2 (0.56) | PIM2PIM1KMODHODHABL1 | |
| SCHEMBL1027774 | 0.73 | GAA (0.45) | MKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL2841145 | 0.71 | GAA (0.43) | MKNK1MKNK2 | |
| SCHEMBL28925103 | 0.71 | MKNK1 (0.49) | MKNK1MKNK2PIM2PIM1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107427699-A | For treating the KDM1A inhibitor of disease | 伊美格生物科学公司 | 2017-12-01 | — | — | CN | disclosed |