Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL698977 | 0.99 | REN (0.60) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL695100 | 0.95 | REN (0.61) | RENCYP3A4 | |
| SCHEMBL9958449 | 0.92 | REN (0.58) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL9958398 | 0.92 | REN (0.57) | RENCYP3A4 | |
| SCHEMBL2818546 | 0.91 | REN (0.60) | RENCYP3A4 | |
| SCHEMBL9959099 | 0.91 | REN (0.51) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL698976 | 0.90 | REN (0.60) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL9959265 | 0.90 | REN (0.51) | RENCYP3A4 | |
| SCHEMBL2792558 | 0.89 | REN (0.66) | RENCYP3A4 | |
| SCHEMBL2788513 | 0.89 | REN (0.77) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122580-A2 | NOVEL COMPOUNDS AS INHIBITORS OF RENIN | CADILA HEALTHCARE LIMITED (IN) | 2010-10-28 | — | — | WO | disclosed |