Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 2/20 | 0.48 |
| ▸ | FLT4 | P35916 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385870 | 0.94 | KDR (0.58) | KDRHPGDRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11771718 | 0.92 | KDR (0.49) | KDRHPGDRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3270536 | 0.88 | MAPK9 (0.51) | KDRHPGDRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23382222 | 0.85 | KDR (0.59) | KDRFLT1FLT4MAPK10MAPK9 | |
| SCHEMBL29975108 | 0.85 | GLA (0.55) | KDRRAB9AMAPK10MAPK9GLA | |
| SCHEMBL28186123 | 0.85 | GLA (0.55) | KDRRAB9AMAPK10MAPK9GLA | |
| SCHEMBL30878105 | 0.85 | KDR (0.59) | KDRFLT1FLT4MAPK10MAPK9 | |
| SCHEMBL3278138 | 0.84 | MAPK9 (0.58) | KDRHPGDRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL12077033 | 0.84 | KDR (0.55) | KDRHPGDRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11091622 | 0.83 | KDR (0.51) | KDRHPGDSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434808-A | A kind of synthetic method of pyridine-imidazole analog derivative and the application in antitumor | 重庆文理学院 | 2017-12-05 | — | — | CN | disclosed |