Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017518 | 0.82 | CHRM2 (0.50) | MEN1KMT2AOPRM1ALDH1A1KDM4E | |
| SCHEMBL28891615 | 0.82 | MEN1 (0.54) | MEN1KMT2AOPRM1ALDH1A1KDM4E | |
| SCHEMBL28001525 | 0.81 | CHRM2 (0.52) | MEN1KMT2AHRH3OPRM1AGER | |
| SCHEMBL28009924 | 0.81 | ALDH1A1 (0.39) | MEN1KMT2AOPRM1ALDH1A1MAPT | |
| SCHEMBL12614459 | 0.81 | CHRM3 (0.52) | MEN1KMT2AHRH3KCNH2ALDH1A1 | |
| SCHEMBL28481666 | 0.80 | PTGIR (0.39) | MEN1KMT2ATSHRNPC1RAB9A | |
| SCHEMBL948515 | 0.80 | SLC6A4 (0.44) | MEN1KMT2ATACR1SLC6A4AGER | |
| SCHEMBL948516 | 0.80 | SLC6A4 (0.44) | MEN1KMT2ATACR1SLC6A4AGER | |
| SCHEMBL949634 | 0.80 | SLC6A4 (0.44) | MEN1KMT2ATACR1SLC6A4AGER | |
| SCHEMBL2362048 | 0.79 | NPC1 (0.45) | MEN1KMT2AOPRM1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114025-B | Nematicide cis (miscellaneous) aryl cyclopropyl carboxamides derivatives | 先正达参股股份有限公司 | 2017-11-07 | — | — | CN | disclosed |