SCHEMBL28186642

SCHEMBL28186642

COC(=O)OC.O=C(Oc1ccccc1)c1ccccc1C(=O)Oc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.61
HSD17B10 Q99714 5/20 0.61
ALOX15 P16050 1/20 0.61
MAPT P10636 5/20 0.58
KDM4E B2RXH2 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
ALDH1A1 P00352 5/20 0.53
KMT2A Q03164 2/20 0.53
XBP1 P17861 1/20 0.51
GLA P06280 1/20 0.50
TSHR P16473 3/20 0.47
NPSR1 Q6W5P4 1/20 0.47
SLC6A3 Q01959 2/20 0.47
LMNA P02545 2/20 0.47
NR4A2 P43354 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CHRM1 P11229 1/20 0.47
TBXA2R P21731 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9340558 0.90 HSD17B10 (0.63) HPGDHSD17B10ALOX15MAPTKDM4E
SCHEMBL29437924 0.88 HSD17B10 (0.76) HPGDHSD17B10ALOX15MAPTKDM4E
SCHEMBL69868 0.88 HSD17B10 (0.76) HPGDHSD17B10ALOX15MAPTKDM4E
SCHEMBL4384041 0.86 HSD17B10 (0.70) HPGDHSD17B10ALOX15MAPTKDM4E
Chloromethane SCHEMBL27696108 0.86 HSD17B10 (0.68) HPGDHSD17B10ALOX15MAPTKDM4E
SCHEMBL28201066 0.86 HPGD (0.68) HPGDHSD17B10ALOX15MAPTKDM4E
Hydrogen Sulfide SCHEMBL28157119 0.86 HSD17B10 (0.73) HPGDHSD17B10ALOX15MAPTKDM4E
Bicarbonate SCHEMBL27452806 0.86 HSD17B10 (0.73) HPGDHSD17B10ALOX15MAPTKDM4E
Methane SCHEMBL27316738 0.86 HSD17B10 (0.73) HPGDHSD17B10ALOX15MAPTKDM4E
Phosphine SCHEMBL28084508 0.86 HSD17B10 (0.73) HPGDHSD17B10ALOX15MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107308984-A It is a kind of to be used for dimethyl carbonate and the immobilized organotin catalysts of silica and preparation method of phenol ester exchange 中国科学院成都有机化学有限公司 2017-11-03 CN disclosed