Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 7/20 | 0.37 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.36 |
| ▸ | CDK9 | P50750 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 3/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292355 | 0.80 | CLK1 (0.46) | IMPDH2HASPINPRMT3CLK1CSNK1D | |
| SCHEMBL21441606 | 0.77 | BRD4 (0.39) | — | |
| SCHEMBL13193051 | 0.73 | PRKCZ (0.40) | IMPDH2HASPINPRMT3CLK1CSNK1D | |
| SCHEMBL19068654 | 0.73 | PRKCZ (0.40) | IMPDH2HASPINPRMT3CLK1CSNK1D | |
| SCHEMBL8272676 | 0.72 | — | — | |
| SCHEMBL6270080 | 0.72 | — | — | |
| SCHEMBL24165351 | 0.72 | DAO (0.43) | IMPDH2HASPINPRMT3CLK1CSNK1D | |
| SCHEMBL2804838 | 0.72 | HASPIN (0.49) | IMPDH2HASPINPRMT3CLK1CSNK1D | |
| SCHEMBL13705844 | 0.72 | HASPIN (0.42) | IMPDH2HASPINPRMT3CLK1CSNK1D | |
| SCHEMBL8286954 | 0.72 | CYP19A1 (0.46) | IMPDH2HASPINPRMT3CLK1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428692-A | Substituted monoazanaphthalene derivatives and polyazanaphthalene derivatives and use thereof | 巴斯利尔药物国际股份公司 | 2017-12-01 | — | — | CN | disclosed |