Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415181 | 1.00 | MAPT (0.44) | MAPTCA12CA9CA1CA2 | |
| SCHEMBL27917674 | 0.83 | CA12 (0.45) | MAPTCA12CA9CA1CA2 | |
| SCHEMBL28688578 | 0.83 | CYP3A4 (0.53) | MAPTMEN1KMT2ARAPGEF4TSHR | |
| SCHEMBL19252495 | 0.83 | RAPGEF4 (0.46) | MAPTCA12CA9CA1CA2 | |
| SCHEMBL31279021 | 0.83 | RAPGEF4 (0.46) | MAPTCA12CA9CA1CA2 | |
| SCHEMBL9571999 | 0.80 | SLC22A12 (0.46) | MAPTCA12CA9CA1CA2 | |
| SCHEMBL5734067 | 0.78 | RARB (0.42) | MAPTCA12CA9CA1CA2 | |
| SCHEMBL29659123 | 0.77 | MAPT (0.46) | MAPTMEN1PABPC1KMT2ARAPGEF4 | |
| SCHEMBL566097 | 0.77 | MAPT (0.53) | MAPTCA12CA9CA1CA2 | |
| SCHEMBL631579 | 0.77 | MAPT (0.46) | MAPTMEN1PABPC1KMT2ARAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336829-B | Aryl formamide compound containing 1,2, 3-triazole structure and application thereof | 沈阳药科大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-109336829-A | Aryl methanamide compounds of the triazole structure containing 1,2,3- and application thereof | 沈阳药科大学 | 2019-02-15 | — | — | CN | disclosed |
| CN-107459491-A | Benzamide compound containing 1,2,3 triazole structures and application thereof | 沈阳药科大学 | 2017-12-12 | — | — | CN | disclosed |