Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | HTR3A | P46098 | 1/20 | 0.68 |
| ▸ | ATR | Q13535 | 2/20 | 0.47 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.47 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722866 | 0.81 | GAA (0.68) | GAAHTR3AATRATRIPPIM1 | |
| SCHEMBL15830277 | 0.81 | GAA (0.68) | GAAHTR3AATRATRIPPIM1 | |
| SCHEMBL1041841 | 0.81 | GAA (1.00) | GAAHTR3AATRATRIPPIM1 | |
| SCHEMBL29495981 | 0.81 | GAA (0.68) | GAAHTR3AATRATRIPPIM1 | |
| SCHEMBL15935202 | 0.81 | GAA (0.63) | GAAHTR3AATRATRIPPIM1 | |
| SCHEMBL31509773 | 0.80 | CCNC (0.54) | GAAHTR3AATRATRIPSMPD3 | |
| SCHEMBL27191954 | 0.80 | CCNC (0.54) | GAAHTR3AATRATRIPSMPD3 | |
| SCHEMBL16891612 | 0.78 | GAA (0.63) | GAAHTR3AATRATRIPPIM1 | |
| SCHEMBL28722011 | 0.77 | GAA (0.62) | GAAHTR3AATRATRIPPIM1 | |
| SCHEMBL29496052 | 0.77 | GAA (0.62) | GAAHTR3AATRATRIPPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107398300-A | The method of the direct ammoxidation of aromatic amides aromatic ring C H keys | 中国科学院化学研究所 | 2017-11-28 | — | — | CN | disclosed |