Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | ATR | Q13535 | 2/20 | 0.43 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496052 | 1.00 | GAA (0.62) | GAAATRATRIPPIM1PIM2 | |
| SCHEMBL28722866 | 0.94 | GAA (0.68) | GAAATRATRIPPIM1PIM2 | |
| SCHEMBL29495981 | 0.94 | GAA (0.68) | GAAATRATRIPPIM1PIM2 | |
| SCHEMBL29495994 | 0.87 | GAA (0.49) | GAAHTR3ABACE1KDM4EMAPT | |
| SCHEMBL28722001 | 0.87 | GAA (0.49) | GAAHTR3ABACE1KDM4EMAPT | |
| SCHEMBL29495968 | 0.80 | GAA (0.50) | GAAATRATRIPPIM1CNR2 | |
| SCHEMBL15830277 | 0.77 | GAA (0.68) | GAAATRATRIPPIM1PIM2 | |
| SCHEMBL3299921 | 0.77 | HTR3A (0.58) | GAAHTR3ABACE1KDM4EALDH1A1 | |
| SCHEMBL1041841 | 0.77 | GAA (1.00) | GAAATRATRIPPIM1PIM2 | |
| SCHEMBL28187656 | 0.77 | GAA (0.68) | GAAATRATRIPPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |