Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28188008 | 0.78 | CYP2D6 (0.44) | HTR1AHTR2AHTR2BDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL4453175 | 0.74 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL3563940 | 0.73 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28969434 | 0.72 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9675386 | 0.72 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3HTR2A | |
| Hydrochloric Acid SCHEMBL4323836 | 0.72 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL28229736 | 0.71 | MAPK11 (0.45) | SLC6A4DRD2DRD4DRD3 | |
| SCHEMBL28188011 | 0.71 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3ADRB2 | |
| SCHEMBL3869571 | 0.69 | DRD2 (0.64) | HTR2ADRD2DRD4DRD3 | |
| SCHEMBL25732230 | 0.69 | DRD2 (0.43) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107405333-A | Substituted pyrazole compound as serpin | 维颂公司 | 2017-11-28 | — | — | CN | disclosed |