Betamethasone Dipropionate

SCHEMBL28188104

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C.CCCCC(=O)O[C@]1(C(=O)CO)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

NR3C1

The experimentally established mechanism targets of Betamethasone Dipropionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	NR3C1 known ✓	P04150	11/20	0.88

▸	PGR	P06401	5/20	0.88

▸	CYP3A4	P08684	5/20	0.88

▸	USP2	O75604	5/20	0.88

▸	MEN1	O00255	1/20	0.88

▸	KMT2A	Q03164	1/20	0.88

▸	NR1I2	O75469	2/20	0.86

▸	MAPT	P10636	2/20	0.86

▸	ADORA3	P0DMS8	2/20	0.86

▸	DRD2	P14416	1/20	0.86

▸	OPRD1	P41143	1/20	0.86

▸	LMNA	P02545	2/20	0.73

▸	MLNR	O43193	1/20	0.73

▸	ABCB11	O95342	1/20	0.73

▸	CYP3A5	P20815	1/20	0.73

▸	PPARG	P37231	1/20	0.73

▸	SMN1; SMN2	Q16637	1/20	0.73

▸	NPSR1	Q6W5P4	1/20	0.73

▸	CYP2D6	P10635	1/20	0.73

▸	CYP2C9	P11712	1/20	0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11520052	0.96	NR3C1 (0.90)	NR3C1PGRCYP3A4USP2MEN1
SCHEMBL4888415	0.94	NR3C1 (0.86)	NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL9768484	0.94	NR3C1 (1.00)	NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL16243364	0.94	NR3C1 (1.00)	NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL11051241	0.94	NR3C1 (1.00)	NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL14339612	0.94	NR3C1 (1.00)	NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL221479	0.94	NR3C1 (1.00)	NR3C1PGRCYP3A4USP2MEN1
Dexamethasone Valarate SCHEMBL124723	0.94	NR3C1 (1.00)	NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL7564753	0.94	NR3C1 (1.00)	NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL9768470	0.94	NR3C1 (1.00)	NR3C1PGRCYP3A4USP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-107405288-A	The polymer of itaconic acid and its purposes in cosmetic product or personal care product as film forming agent	伊塔康尼克（英国）有限公司	2017-11-28	—	—	CN	disclosed