Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28187874 | 0.85 | KLK7 (0.49) | SLC18A3CYP3A4PIK3CDPREPFAP | |
| SCHEMBL28188448 | 0.85 | SLC18A3 (0.52) | SLC18A3GAAACKR3PIK3CDSMN1; SMN2 | |
| SCHEMBL13391062 | 0.82 | SLC18A3 (0.63) | SLC18A3GAASMN1; SMN2TDP1 | |
| SCHEMBL18228117 | 0.82 | SLC18A3 (0.54) | SLC18A3GAAPREPFAPTDP1 | |
| SCHEMBL7447435 | 0.80 | SLC18A3 (0.58) | SLC18A3GAASMN1; SMN2GRM1 | |
| SCHEMBL18228260 | 0.80 | SLC18A3 (0.57) | SLC18A3GAASMN1; SMN2TDP1KLK7 | |
| SCHEMBL28188540 | 0.79 | MGLL (0.41) | SLC18A3MGLL | |
| SCHEMBL16655882 | 0.78 | SLC18A3 (0.56) | SLC18A3GAACYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL28853725 | 0.78 | SMYD3 (0.44) | GAACYP3A4ACKR3TDP1MGLL | |
| SCHEMBL15646467 | 0.78 | SLC18A3 (0.58) | SLC18A3GAAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635986-A | Substituted quinoxaline derivatives | 赛尔维他股份公司 | 2018-01-26 | — | — | CN | disclosed |