Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3700826 | 0.82 | GSK3B (0.46) | GSK3B | |
| SCHEMBL3700830 | 0.82 | GSK3B (0.46) | GSK3B | |
| SCHEMBL24342636 | 0.79 | GSK3B (0.45) | GSK3B | |
| SCHEMBL3273432 | 0.79 | GSK3B (0.46) | GSK3B | |
| SCHEMBL3273438 | 0.79 | GSK3B (0.46) | GSK3B | |
| SCHEMBL188499 | 0.79 | KDM4E (0.38) | GSK3BKMT2A | |
| SCHEMBL1777416 | 0.79 | GSK3B (0.46) | GSK3B | |
| SCHEMBL24547769 | 0.79 | EPHX2 (0.43) | HTR2CMEN1KMT2A | |
| SCHEMBL2908444 | 0.78 | PDE10A (0.45) | GSK3B | |
| SCHEMBL90572 | 0.78 | PDE10A (0.45) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452233-B | Piperidine and azepane derivatives as prokineticin receptor modulators | 武田药品工业株式会社 | 2017-12-08 | — | — | CN | disclosed |