Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28159884 | 0.87 | GLS (0.48) | GLSMAPTNOS1POLBMAOB | |
| SCHEMBL18188106 | 0.80 | GLS (0.58) | GLSMAPTNOS1POLBMAOB | |
| SCHEMBL19969336 | 0.80 | GLS (0.58) | GLSMAPTNOS1POLBMAOB | |
| SCHEMBL2350364 | 0.80 | GLS (0.58) | GLSMAPTNOS1POLBMAOB | |
| SCHEMBL30716437 | 0.80 | GLS (0.58) | GLSMAPTNOS1POLBMAOB | |
| SCHEMBL271762 | 0.80 | GLS (0.62) | GLSMAPTNOS1POLBMAOB | |
| SCHEMBL4762417 | 0.80 | GLS (0.58) | GLSMAPTNOS1POLBMAOB | |
| SCHEMBL9555018 | 0.80 | GLS (0.58) | GLSMAPTNOS1POLBMAOB | |
| SCHEMBL29661255 | 0.80 | GLS (0.62) | GLSMAPTNOS1POLBMAOB | |
| SCHEMBL27985287 | 0.80 | GLS (0.62) | GLSMAPTNOS1POLBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586432-B | 3- (indole-5-yl) -indazole derivative and application thereof | 温州医科大学 | 2020-08-25 | — | — | CN | disclosed |
| CN-109121414-A | Benzopyrazole compounds and analogs thereof | 拜奥克里斯特制药公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-108586432-A | A kind of 3-（Indoles -5- bases）Indazole derivative and its application | 温州医科大学 | 2018-09-28 | — | — | CN | disclosed |
| CN-104470925-B | Imidazo-triazine formonitrile HCN as kinase inhibitor | 百时美施贵宝公司 | 2017-12-05 | — | — | CN | disclosed |