Thidiazuron

Thidiazuron

SCHEMBL28190056

O=C(Nc1ccccc1)Nc1cnns1.O=[SH](=O)O.c1cncnc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.42
TP53 P04637 2/20 0.42
EPHX1 P07099 1/20 0.42
TSHR P16473 1/20 0.42
EPHX2 P34913 1/20 0.42
CDK9 P50750 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
RAB9A P51151 6/20 0.40
NPC1 O15118 5/20 0.40
PKM P14618 1/20 0.40
IMPDH2 P12268 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
PIM1 P11309 2/20 0.40
AURKA O14965 1/20 0.40
CDK2 P24941 1/20 0.40
GSK3B P49841 1/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thidiazuron SCHEMBL27787530 0.95 TAAR1 (0.51) TAAR1SMN1; SMN2TP53EPHX1TSHR
Thidiazuron SCHEMBL1808496 0.87 SMN1; SMN2 (0.57) TAAR1SMN1; SMN2TP53EPHX1TSHR
Thidiazuron SCHEMBL121077 0.87 SMN1; SMN2 (0.57) TAAR1SMN1; SMN2TP53EPHX1TSHR
Thidiazuron SCHEMBL20723866 0.85 SMN1; SMN2 (0.55) TAAR1SMN1; SMN2TP53EPHX1TSHR
Thidiazuron SCHEMBL15553871 0.85 SMN1; SMN2 (0.55) TAAR1SMN1; SMN2TP53EPHX1TSHR
SCHEMBL11643580 0.81 RAB9A (0.56) TAAR1TSHRRAB9ANPC1PKM
Thidiazuron SCHEMBL27797671 0.81 SMN1; SMN2 (0.44) TAAR1SMN1; SMN2TP53EPHX1TSHR
SCHEMBL11646588 0.80 MDM2 (0.61) TAAR1SMN1; SMN2RAB9APKMMEN1
Thidiazuron SCHEMBL2315650 0.77 TP53 (0.45) TAAR1SMN1; SMN2TP53EPHX1TSHR
Thidiazuron SCHEMBL28791580 0.75 CA12 (0.43) TAAR1SMN1; SMN2TP53EPHX1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107427008-A Pesticidal combination and correlation technique 美国陶氏益农公司 2017-12-01 CN disclosed