Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18698080 | 0.84 | KDM4E (0.69) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11825482 | 0.83 | LMNA (0.58) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL12033647 | 0.83 | MEN1 (0.53) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL422358 | 0.81 | PDE10A (0.61) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL26858214 | 0.80 | KMT2A (0.56) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL15483476 | 0.80 | MAPT (0.57) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL19449104 | 0.80 | CYP1A2 (0.68) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL17904147 | 0.79 | NR1I3 (0.68) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19169418 | 0.78 | PDE10A (0.60) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL16404298 | 0.78 | ABCG2 (0.72) | LMNAKDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418516-B | A kind of quinazoline compounds and preparation method thereof | 信阳师范学院 | 2018-03-02 | — | — | CN | disclosed |
| CN-105327703-B | The preparation method of gold nano catalyst and the catalyst prod obtained and application | 中国科学技术大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-105418516-A | Quinazoline compounds and preparation method thereof | UNIV XINYANG NORMAL | 2016-03-23 | — | — | CN | disclosed |
| CN-105327703-A | Preparation method for gold nanometer catalyst, and obtained catalyst product and application thereof | USTC UNIV SCIENCE TECH CN | 2016-02-17 | — | — | CN | disclosed |