Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 2/20 | 0.35 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | STK16 | O75716 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.35 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30610404 | 0.80 | NQO2 (0.39) | MAOANQO2ALOX5APFEN1CA2 | |
| SCHEMBL26233588 | 0.79 | HPGD (0.43) | MAOACA2TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1899766 | 0.78 | NQO2 (0.38) | MAOANQO2ALOX5APFEN1CA2 | |
| SCHEMBL2067547 | 0.78 | LRRK2 (0.36) | MAOACYP2A6 | |
| SCHEMBL10819312 | 0.77 | MAOA (0.52) | MAOATGFBR1CCR1CCR5CCR8 | |
| SCHEMBL25283372 | 0.77 | NQO2 (0.37) | MAOANQO2ALOX5APFEN1CA2 | |
| SCHEMBL28834729 | 0.77 | NQO2 (0.37) | MAOANQO2ALOX5APFEN1CA2 | |
| SCHEMBL3711280 | 0.77 | ALOX5AP (0.41) | MAOANQO2ALOX5APFEN1CA2 | |
| SCHEMBL30527538 | 0.77 | ALOX5AP (0.41) | MAOANQO2ALOX5APFEN1CA2 | |
| SCHEMBL27593317 | 0.77 | NQO2 (0.37) | MAOANQO2ALOX5APFEN1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107548389-A | Cyclopropanecarboxylic acid derivatives and pharmaceutical use thereof | 阿斯利康(瑞典)有限公司 | 2018-01-05 | — | — | CN | disclosed |