Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820308 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1HPGDGPR35 | |
| SCHEMBL28796972 | 0.80 | BID (0.43) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL9820277 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1HPGDGPR35 | |
| SCHEMBL28003051 | 0.79 | BID (0.46) | ALDH1A1TSHRTDP1MAPTKDM4E | |
| SCHEMBL19764227 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1HPGDGPR35 | |
| SCHEMBL994423 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TSHRTDP1HPGDGPR35 | |
| SCHEMBL6278459 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1HPGDGPR35 | |
| SCHEMBL2416170 | 0.75 | TDP1 (0.50) | ALDH1A1TSHRTDP1HPGDGPR35 | |
| SCHEMBL28160982 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HPGDSIGMAR1 | |
| SCHEMBL28190370 | 0.74 | TDP1 (0.42) | ALDH1A1TSHRTDP1HPGDGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392787-B | For treating and preventing the azepine oxindole of respiratory syncytial virus infection | 豪夫迈·罗氏有限公司 | 2017-11-24 | — | — | CN | disclosed |