Phenazine

Phenazine

SCHEMBL28190824

c1ccc2nc3ccccc3nc2c1.c1ccsc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.65
NQO2 P16083 6/20 0.50
KMT2A Q03164 3/20 0.46
NPC1 O15118 3/20 0.46
MEN1 O00255 2/20 0.46
POLB P06746 2/20 0.46
USP2 O75604 1/20 0.46
CACNA1B Q00975 1/20 0.46
APBA1 Q02410 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 7/20 0.46
HPGD P15428 4/20 0.46
KDM4E B2RXH2 4/20 0.46
GAA P10253 3/20 0.46
HSD17B10 Q99714 3/20 0.46
GLA P06280 2/20 0.46
ACHE P22303 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
RAB9A P51151 4/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenazine SCHEMBL29186435 1.00 MAPT (0.65) MAPTNQO2KMT2ANPC1MEN1
Acridine SCHEMBL28156525 0.85 ALDH1A1 (0.71) MAPTNQO2KMT2ANPC1MEN1
Acridine SCHEMBL11757220 0.83 ALDH1A1 (0.68) MAPTNQO2KMT2ANPC1MEN1
Phenazine SCHEMBL9049 0.80 MAPT (1.00) MAPTNQO2KMT2ANPC1MEN1
Phenazine SCHEMBL29356959 0.80 MAPT (1.00) MAPTNQO2KMT2ANPC1MEN1
Phenazine SCHEMBL27643128 0.80 MAPT (1.00) MAPTNQO2KMT2ANPC1MEN1
Naphthalene SCHEMBL28492619 0.79 CYP2A6 (0.50) MAPTNQO2ALDH1A1HSD17B10TDP1
Quinoxaline SCHEMBL4885765 0.78 ALDH1A1 (0.44) MAPTKMT2ANPC1MEN1POLB
Quinoxaline SCHEMBL1336553 0.78 ALDH1A1 (0.44) MAPTKMT2ANPC1MEN1POLB
Benzo[1,2,5]Thiadiazole SCHEMBL3841622 0.78 MAPT (0.41) MAPTKMT2ANPC1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107698999-B One kind having (D-D- π-A)3Phenothiazine dyes of structure and its preparation method and application 江西农业大学 2019-05-17 CN disclosed
CN-107698999-A One kind has (D D π A)3Phenothiazine dyes of structure and its preparation method and application 江西农业大学 2018-02-16 CN disclosed